Title Intracellular signaling pathways for vitellogenin synthesis in the ovary of the kuruma prawn, Penaeus (Marsupenaeus) japonicus
Authers Takuji OKUMURA
Keywords hormone, Kuruma prawn, signaling, vitellogenin
Citation Bull. Fish. Res. Agen. No.26, 135-141, 2008
Abstract
In penaeid shrimp species, vitellogenin (Vg) synthesis in the ovary is under the inhibitory regulation of vitellogenesis-inhibiting hormone (VIH) secreted from a neuroendocrine system, the X-organ/sinus gland complex in the eyestalks. In this manuscript, I review my work on intracellular signaling pathways for vitellogenin synthesis in the ovary of the kuruma prawn, Penaeus (Marsupenaeus) japonicus. The effects of pharmacological agents on Vg mRNA levels in incubated shrimp ovarian fragments indicate that cyclic nucleotides, Ca2+ , and protein kinase C are involved in the signaling pathways for vitellogenin synthesis in the ovary. Furthermore, previtellogenic ovaries showed larger inhibitory effects of pharmacological agents than vitellogenic ovaries. This result suggests that the responsiveness of signaling pathways for vitellogenin synthesis changes during ovarian development.
URI http://www.fra.affrc.go.jp/bulletin/bull/bull26/okumura.pdf